Morphological imaging and T2 and T2* mapping of hip cartilage at 7 Tesla MRI under the influence of intravenous gadolinium.
Eur Radiol
; 26(11): 3923-3931, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-26873493
ABSTRACT
OBJECTIVES:
To investigate the influence of intravenous gadolinium on cartilage T2 and T2* relaxation times and on morphological image quality at 7-T hip MRI.METHODS:
Hips of 11 healthy volunteers were examined at 7 T. Multi-echo sequences for T2 and T2* mapping, 3D T1 volumetric interpolated breath-hold examination (VIBE) and double-echo steady-state (DESS) sequences were acquired before and after intravenous application of gadolinium according to a delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) protocol. Cartilage relaxation times were measured in both scans. Morphological sequences were assessed quantitatively using contrast ratios and qualitatively using a 4-point Likert scale. Student's t-test, Pearson's correlation (ρ) and Wilcoxon sign-rank test were used for statistical comparisons.RESULTS:
Pre- and post-contrast T2 and T2* values were highly correlated (T2 acetabular ρ = 0.76, femoral ρ = 0.77; T2* acetabular ρ = 0.80, femoral ρ = 0.72). Gadolinium enhanced contrasts between cartilage and joint fluid in DESS and T1 VIBE according to the qualitative (p = 0.01) and quantitative (p < 0.001) analysis. The delineation of acetabular and femoral cartilage and the labrum predominantly improved with gadolinium.CONCLUSIONS:
Gadolinium showed no relevant influence on T2 or T2* relaxation times and improved morphological image quality at 7 T. Therefore, morphological and quantitative sequences including dGEMRIC can be conducted in a one-stop-shop examination. KEY POINTS ⢠Hip cartilage T2 values correlate highly before and after gadolinium at 7 T ⢠Hip cartilage T2* values correlate highly before and after enhancement at 7 T ⢠Morphological hip cartilage imaging benefits from intravenous gadolinium at 7 T ⢠The delineation of acetabular and femoral cartilage can be improved by gadolinium ⢠Morphological and quantitative sequences including dGEMRIC can be combined as a one-stop-shop examination.Palavras-chave
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Bases de dados:
MEDLINE
Assunto principal:
Cartilagem Articular
/
Meios de Contraste
/
Gadolínio DTPA
Tipo de estudo:
Qualitative_research
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Alemanha