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A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy.
Eng, Cathy; Bessudo, Alberto; Hart, Lowell L; Severtsev, Aleksey; Gladkov, Oleg; Müller, Lothar; Kopp, Mikhail V; Vladimirov, Vladimir; Langdon, Robert; Kotiv, Bogdan; Barni, Sandro; Hsu, Ching; Bolotin, Ellen; von Roemeling, Reinhard; Schwartz, Brian; Bendell, Johanna C.
Afiliação
  • Eng C; The University of Texas M.D. Anderson Cancer Center, Houston, TX.
  • Bessudo A; cCARE (California Cancer Associates for Research & Excellence), Encinitas, CA.
  • Hart LL; Florida Cancer Specialists/Sarah Cannon Research Institute, Fort Myers, FL.
  • Severtsev A; The Central Clinical Hospital #1, Moscow, Russia.
  • Gladkov O; Chelyabinsk Regional Clinical Oncological Dispensary, Chelyabinsk, Russia.
  • Müller L; Onkologie Untere Ems Leer-Emden-Papenburg, Leer, Germany.
  • Kopp MV; Samara Regional Clinical Oncology Dispensary, Samara, Russia.
  • Vladimirov V; Pyatigorsk Oncological Dispensary, Pyatigorsk, Russia.
  • Langdon R; Nebraska Methodist Hospital Cancer Center, Omaha, NE.
  • Kotiv B; Military Medical Academy, Saint Petersburg, Russia.
  • Barni S; Azienda Ospedaliera Treviglio, Treviglio, BG, Italy.
  • Hsu C; Daiichi Sankyo, Inc, Edison, NJ.
  • Bolotin E; Bayer HealthCare, Whippany, NJ, (Employed at Daiichi Sankyo, Inc. At Time of Manuscript Preparation).
  • von Roemeling R; Daiichi Sankyo, Inc, Edison, NJ.
  • Schwartz B; ArQule, Inc, Burlington, MA.
  • Bendell JC; Tennessee Oncology/Sarah Cannon Research Institute, Nashville, TN.
Int J Cancer ; 139(1): 177-86, 2016 Jul 01.
Article em En | MEDLINE | ID: mdl-26891420
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirrolidinonas / Quinolinas / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirrolidinonas / Quinolinas / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Ano de publicação: 2016 Tipo de documento: Article