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Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT.
Tièche, Colin Charles; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph Alexander; Marti, Thomas Michael.
Afiliação
  • Tièche CC; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. colin.tieche@insel.ch.
  • Peng RW; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. renwang.peng@insel.ch.
  • Dorn P; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. Patrick.dorn@insel.ch.
  • Froment L; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. laurene.froment@insel.ch.
  • Schmid RA; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. ralph.schmid@insel.ch.
  • Marti TM; Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Department of Clinical Research, University of Bern, Murtenstrasse 50, 3008, Bern, Switzerland. thomas.marti@insel.ch.
BMC Cancer ; 16: 125, 2016 Feb 19.
Article em En | MEDLINE | ID: mdl-26895954

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dano ao DNA / Cisplatino / Carcinoma Pulmonar de Células não Pequenas / Pemetrexede / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dano ao DNA / Cisplatino / Carcinoma Pulmonar de Células não Pequenas / Pemetrexede / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça