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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz, Semir; Mana, Miyeko D; Roper, Jatin; Kedrin, Dmitriy; Saadatpour, Assieh; Hong, Sue-Jean; Bauer-Rowe, Khristian E; Xifaras, Michael E; Akkad, Adam; Arias, Erika; Pinello, Luca; Katz, Yarden; Shinagare, Shweta; Abu-Remaileh, Monther; Mihaylova, Maria M; Lamming, Dudley W; Dogum, Rizkullah; Guo, Guoji; Bell, George W; Selig, Martin; Nielsen, G Petur; Gupta, Nitin; Ferrone, Cristina R; Deshpande, Vikram; Yuan, Guo-Cheng; Orkin, Stuart H; Sabatini, David M; Yilmaz, Ömer H.
Afiliação
  • Beyaz S; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Mana MD; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Roper J; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Kedrin D; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Saadatpour A; Division of Gastroenterology and Molecular Oncology Research Institute, Tufts Medical Center, Boston, Massachusetts 02111, USA.
  • Hong SJ; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Bauer-Rowe KE; Departments of Pathology, Gastroenterology, and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Xifaras ME; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Akkad A; Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, Massachusetts 02142, USA.
  • Arias E; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Pinello L; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Katz Y; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Shinagare S; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Abu-Remaileh M; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Mihaylova MM; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Lamming DW; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Dogum R; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Guo G; Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, Massachusetts 02142, USA.
  • Bell GW; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Selig M; Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, Massachusetts 02142, USA.
  • Nielsen GP; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA.
  • Gupta N; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, Massachusetts 02139, USA.
  • Ferrone CR; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Deshpande V; Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, Massachusetts 02142, USA.
  • Yuan GC; Departments of Pathology, Gastroenterology, and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Orkin SH; Departments of Pathology, Gastroenterology, and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Sabatini DM; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Missisippi 39216, USA.
  • Yilmaz ÖH; Departments of Pathology, Gastroenterology, and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
Nature ; 531(7592): 53-8, 2016 Mar 03.
Article em En | MEDLINE | ID: mdl-26935695
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células-Tronco / Transformação Celular Neoplásica / Neoplasias do Colo / Dieta Hiperlipídica / Intestinos Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células-Tronco / Transformação Celular Neoplásica / Neoplasias do Colo / Dieta Hiperlipídica / Intestinos Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos