Splenic angiomyxoma with intravascular tumor embolus in a dog: a case report.
J Vet Med Sci
; 78(6): 1085-8, 2016 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-26972144
ABSTRACT
A 13-year-old castrated male Yorkshire terrier dog had a soft splenic mass, which measured 11 cm in the greatest diameter. Microscopically, the parenchyma of the spleen was completely replaced by myxoid substances. Numerous spindle and stellate cells were loosely arranged in the myxoid stroma, and variable vessels of variable sizes were observed in a loose matrix with poorly defined margins. Immunohistochemical analysis showed that tumor cells were positive for desmin and alpha-SMA, but negative for S-100. Interestingly, intravascular tumor embolus with positive α-SMA expression was observed. This case is meaningful, because angiomyxoma, a rare tumor of dogs, occurs in the spleen. Even in human cases, splenic angiomyxoma was not reported.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Esplênicas
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Doenças do Cão
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Mixoma
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Células Neoplásicas Circulantes
Limite:
Animals
Idioma:
En
Revista:
J Vet Med Sci
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2016
Tipo de documento:
Article