[Immune tolerance mechanisms--brief review]. / Krótka charakterystyka mechanizmów tolerancji immunologicznej.
Przegl Lek
; 72(12): 765-9, 2015.
Article
em Pl
| MEDLINE
| ID: mdl-27024957
ABSTRACT
The purpose of the immune system is not only to fight off pathogens but also to keep a tolerance to self-antigens. In central tolerance, major mechanisms include apoptosis (for T cells) and receptor editing (for B cells). Regulatory T cells appear to be the most important in peripheral tolerance. Innate immune cells also influence the maintenance of immune tolerance. We have provided an overall review of all these mechanisms. Successful restoration of the immune tolerance is the target of new strategies in autoimmune diseases therapy.
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Bases de dados:
MEDLINE
Assunto principal:
Linfócitos B
/
Linfócitos T
/
Tolerância Imunológica
Limite:
Humans
Idioma:
Pl
Revista:
Przegl Lek
Ano de publicação:
2015
Tipo de documento:
Article