An unusual sesquiterpene coumarin from the seeds of Ferula sinkiangensis.
J Asian Nat Prod Res
; 18(9): 891-6, 2016 Sep.
Article
em En
| MEDLINE
| ID: mdl-27053285
ABSTRACT
A sesquiterpene coumarin, sinkiangenorin E, consisting of a novel bicyclo[4.3.1]decane-type sesquiterpene system, was isolated from the seeds of Ferula sinkiangensis. The structure of sinkiangenorin E including the relative stereochemistry and the absolute configuration was elucidated on the basis of spectroscopic data. The new compound showed cytotoxic activity against AGS cells (IC50, 12.7 µM) and inhibiting effect against influenza A H1N1 (IC50, 4.0 µM), which provided important clues for the study on the bioactivities of this type of sesquiterpene coumarins.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Medicamentos de Ervas Chinesas
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Cumarínicos
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Ferula
Limite:
Humans
Idioma:
En
Revista:
J Asian Nat Prod Res
Assunto da revista:
BOTANICA
/
QUIMICA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
China