Three cases of thyroid cancer following the diagnosis of testicular cancer: treatment-related complication or genetics?
Scott Med J
; 61(2): 111-116, 2016 May.
Article
em En
| MEDLINE
| ID: mdl-27069005
ABSTRACT
Large-scale epidemiological studies have shown that the incidence of second primary thyroid cancer in subjects diagnosed and treated for testicular cancer is raised. This finding is strongly associated to treatment with radiotherapy and/or chemotherapy and it is explained by their mutagenic effect. On the other hand, inherited cancer susceptibility syndromes inducing both testicular and thyroid cancers denote that these tumours might share common genomic aberrations. We herein present our experience with three cases of metachronous development of thyroid cancer after diagnosis and treatment of testicular cancer in our tertiary cancer centre. Our case report contributes to the limited available literature on such findings and aims to raise awareness of the cancer physicians treating these particular tumour types.
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Bases de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
/
Carcinoma
/
Segunda Neoplasia Primária
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Scott Med J
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Reino Unido