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Unnatural amino acid analogues of membrane-active helical peptides with anti-mycobacterial activity and improved stability.
Khara, Jasmeet Singh; Priestman, Miles; Uhía, Iria; Hamilton, Melissa Shea; Krishnan, Nitya; Wang, Ying; Yang, Yi Yan; Langford, Paul R; Newton, Sandra M; Robertson, Brian D; Ee, Pui Lai Rachel.
Afiliação
  • Khara JS; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, UK MRC Centre for Molecular Microbiology and Infection, Department of Medicine, Imperial
  • Priestman M; MRC Centre for Molecular Microbiology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Uhía I; MRC Centre for Molecular Microbiology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Hamilton MS; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Krishnan N; MRC Centre for Molecular Microbiology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Wang Y; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore.
  • Yang YY; Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, Singapore 138669, Singapore.
  • Langford PR; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Newton SM; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Robertson BD; MRC Centre for Molecular Microbiology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Ee PL; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore phaeplr@nus.edu.sg.
J Antimicrob Chemother ; 71(8): 2181-91, 2016 08.
Article em En | MEDLINE | ID: mdl-27118774
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos / Aminoácidos / Proteínas de Membrana / Mycobacterium tuberculosis / Antituberculosos Limite: Animals Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos / Aminoácidos / Proteínas de Membrana / Mycobacterium tuberculosis / Antituberculosos Limite: Animals Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2016 Tipo de documento: Article