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Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity.
Eichner, Ruth; Heider, Michael; Fernández-Sáiz, Vanesa; van Bebber, Frauke; Garz, Anne-Kathrin; Lemeer, Simone; Rudelius, Martina; Targosz, Bianca-Sabrina; Jacobs, Laura; Knorn, Anna-Maria; Slawska, Jolanta; Platzbecker, Uwe; Germing, Ulrich; Langer, Christian; Knop, Stefan; Einsele, Herrmann; Peschel, Christian; Haass, Christian; Keller, Ulrich; Schmid, Bettina; Götze, Katharina S; Kuster, Bernhard; Bassermann, Florian.
Afiliação
  • Eichner R; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Heider M; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Fernández-Sáiz V; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • van Bebber F; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Garz AK; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lemeer S; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Rudelius M; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Targosz BS; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Jacobs L; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Knorn AM; Department of Proteomics and Bioanalytics, Technische Universität München, Freising, Germany.
  • Slawska J; Institute of Pathology, Universität Würzburg, Würzburg, Germany.
  • Platzbecker U; Comprehensive Cancer Center Mainfranken, Universität Würzburg, Würzburg, Germany.
  • Germing U; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Langer C; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Knop S; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Einsele H; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Peschel C; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl-Gustav-Carus, Technische Universität, Dresden, Germany.
  • Haass C; Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Düsseldorf, Germany.
  • Keller U; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
  • Schmid B; Division of Hematology and Medical Oncology, Department of Internal Medicine II, Würzburg University Medical Center, Würzburg, Germany.
  • Götze KS; Division of Hematology and Medical Oncology, Department of Internal Medicine II, Würzburg University Medical Center, Würzburg, Germany.
  • Kuster B; Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Bassermann F; German Cancer Consortium (DKTK), Heidelberg, Germany.
Nat Med ; 22(7): 735-43, 2016 07.
Article em En | MEDLINE | ID: mdl-27294876
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Talidomida / RNA Mensageiro / Proteínas Oncogênicas / Proteínas de Ciclo Celular / Basigina / Teratogênese / Fatores Imunológicos / Imunossupressores Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Talidomida / RNA Mensageiro / Proteínas Oncogênicas / Proteínas de Ciclo Celular / Basigina / Teratogênese / Fatores Imunológicos / Imunossupressores Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha