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Role of Myeloma-Derived MIF in Myeloma Cell Adhesion to Bone Marrow and Chemotherapy Response.
Zheng, Yuhuan; Wang, Qiang; Li, Tianshu; Qian, Jianfei; Lu, Yong; Li, Yi; Bi, Enguang; Reu, Frederic; Qin, Yu; Drazba, Judy; Hsi, Eric; Yang, Jing; Cai, Zhen; Yi, Qing.
Afiliação
  • Zheng Y; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Wang Q; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Li T; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Qian J; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Lu Y; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Li Y; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Bi E; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Reu F; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Qin Y; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Drazba J; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Hsi E; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Yang J; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Cai Z; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
  • Yi Q; Affiliations of authors: Department of Hematology and State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, West China Hospital, China (YZ); Department of Cancer Biology (YZ, QW, TL, JQ, YLu, YLi, EB, QY), Taussig Cancer Center (FR), Imaging Core Facility, Lerner Research Institu
J Natl Cancer Inst ; 108(11)2016 11.
Article em En | MEDLINE | ID: mdl-27381622
Assuntos
Resistencia a Medicamentos Antineoplásicos/genética; Oxirredutases Intramoleculares/genética; Oxirredutases Intramoleculares/metabolismo; Fatores Inibidores da Migração de Macrófagos/genética; Fatores Inibidores da Migração de Macrófagos/metabolismo; Mieloma Múltiplo/genética; Mieloma Múltiplo/metabolismo; Plasmócitos/metabolismo; Molécula de Adesão de Leucócito Ativado/genética; Animais; Antígenos de Diferenciação de Linfócitos B/genética; Antígenos de Diferenciação de Linfócitos B/metabolismo; Antineoplásicos Alquilantes/farmacologia; Apoptose/efeitos dos fármacos; Comunicação Autócrina; Medula Óssea/metabolismo; Bortezomib/farmacologia; Complexo do Signalossomo COP9; Adesão Celular/efeitos dos fármacos; Adesão Celular/genética; Linhagem Celular Tumoral; Quimiotaxia/genética; Técnicas de Cocultura; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Feminino; Expressão Gênica; Técnicas de Silenciamento de Genes; Xenoenxertos; Antígenos de Histocompatibilidade Classe II/genética; Antígenos de Histocompatibilidade Classe II/metabolismo; Humanos; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Oxirredutases Intramoleculares/antagonistas & inibidores; Fatores Inibidores da Migração de Macrófagos/antagonistas & inibidores; Melfalan/farmacologia; Células-Tronco Mesenquimais/metabolismo; Camundongos; Camundongos SCID; Mieloma Múltiplo/tratamento farmacológico; Mieloma Múltiplo/patologia; Transplante de Neoplasias; Peptídeo Hidrolases/metabolismo; Pirimidinas/farmacologia; RNA Mensageiro/metabolismo; Receptores CXCR4/genética; Receptores CXCR4/metabolismo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Plasmócitos / Fatores Inibidores da Migração de Macrófagos / Resistencia a Medicamentos Antineoplásicos / Oxirredutases Intramoleculares / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Idioma: En Revista: J Natl Cancer Inst Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Plasmócitos / Fatores Inibidores da Migração de Macrófagos / Resistencia a Medicamentos Antineoplásicos / Oxirredutases Intramoleculares / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Idioma: En Revista: J Natl Cancer Inst Ano de publicação: 2016 Tipo de documento: Article