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An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment.
Xia, Shijin; Zhang, Xinyan; Zheng, Songbai; Khanabdali, Ramin; Kalionis, Bill; Wu, Junzhen; Wan, Wenbin; Tai, Xiantao.
Afiliação
  • Xia S; Department of Geriatrics, Shanghai Institute of Geriatrics, Huadong Hospital, Fudan University, Shanghai 200040, China.
  • Zhang X; Department of Information, Chengdu Military General Hospital, Chengdu 610083, China.
  • Zheng S; Department of Geriatrics, Shanghai Institute of Geriatrics, Huadong Hospital, Fudan University, Shanghai 200040, China.
  • Khanabdali R; Department of Maternal-Fetal Medicine Pregnancy Research Centre and Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, VIC 3052, Australia.
  • Kalionis B; Department of Maternal-Fetal Medicine Pregnancy Research Centre and Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, VIC 3052, Australia.
  • Wu J; Department of Geriatrics, Shanghai Institute of Geriatrics, Huadong Hospital, Fudan University, Shanghai 200040, China.
  • Wan W; Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Tai X; School of Acupuncture, Massage and Rehabilitation, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China.
J Immunol Res ; 2016: 8426874, 2016.
Article em En | MEDLINE | ID: mdl-27493973
ABSTRACT
Inflamm-aging is a challenging and promising new branch of aging-related research fields that includes areas such as immunosenescence. Increasing evidence indicates that inflamm-aging is intensively associated with many aging diseases, such as Alzheimer's disease, atherosclerosis, heart disease, type II diabetes, and cancer. Mounting studies have focused on the role of inflamm-aging in disease progression and many advances have been made in the last decade. However, the underlying mechanisms by which inflamm-aging affects pathological changes and disease development are still unclear. Here, we review studies of inflamm-aging that explore the concept, pathological features, mechanisms, intervention, and the therapeutic strategies of inflamm-aging in disease progression.
Assuntos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Inflamação Limite: Animals / Humans Idioma: En Revista: J Immunol Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Inflamação Limite: Animals / Humans Idioma: En Revista: J Immunol Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China