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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Scharping, Nicole E; Menk, Ashley V; Moreci, Rebecca S; Whetstone, Ryan D; Dadey, Rebekah E; Watkins, Simon C; Ferris, Robert L; Delgoffe, Greg M.
Afiliação
  • Scharping NE; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Menk AV; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA.
  • Moreci RS; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA.
  • Whetstone RD; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Dadey RE; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Watkins SC; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Ferris RL; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Delgoffe GM; Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address: gdelgoffe@pitt.edu.
Immunity ; 45(2): 374-88, 2016 08 16.
Article em En | MEDLINE | ID: mdl-27496732
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T / Linfócitos do Interstício Tumoral / Neoplasias do Colo / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T / Linfócitos do Interstício Tumoral / Neoplasias do Colo / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos