Lack of predictive power of trait fear and anxiety for conditioned pain modulation (CPM).
Exp Brain Res
; 234(12): 3649-3658, 2016 12.
Article
em En
| MEDLINE
| ID: mdl-27566171
ABSTRACT
In recent years the association of conditioned pain modulation (CPM) with trait fear and anxiety has become a hot topic in pain research due to the assumption that such variables may explain the low CPM efficiency in some individuals. However, empirical evidence concerning this association is still equivocal. Our study is the first to investigate the predictive power of fear and anxiety for CPM by using a well-established psycho-physiological measure of trait fear, i.e. startle potentiation, in addition to two self-report measures of pain-related trait anxiety. Forty healthy, pain-free participants (female N = 20; age M = 23.62 years) underwent two experimental blocks in counter-balanced order (1) a startle paradigm with affective picture presentation and (2) a CPM procedure with hot water as conditioning stimulus (CS) and contact heat as test stimulus (TS). At the end of the experimental session, pain catastrophizing (PCS) and pain anxiety (PASS) were assessed. PCS score, PASS score and startle potentiation to threatening pictures were entered as predictors in a linear regression model with CPM magnitude as criterion. We were able to show an inhibitory CPM effect in our sample pain ratings of the heat stimuli were significantly reduced during hot water immersion. However, CPM was neither predicted by self-report of pain-related anxiety nor by startle potentiation as psycho-physiological measure of trait fear. These results corroborate previous negative findings concerning the association between trait fear/anxiety and CPM efficiency and suggest that shifting the focus from trait to state measures might be promising.
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Bases de dados:
MEDLINE
Assunto principal:
Ansiedade
/
Dor
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Condicionamento Psicológico
/
Medo
/
Catastrofização
Tipo de estudo:
Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Exp Brain Res
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Alemanha