Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-ß-d-ribose Oxidase.

Batt, Sarah M; Cacho Izquierdo, Monica; Castro Pichel, Julia; Stubbs, Christopher J; Vela-Glez Del Peral, Laura; Pérez-Herrán, Esther; Dhar, Neeraj; Mouzon, Bernadette; Rees, Mike; Hutchinson, Jonathan P; Young, Robert J; McKinney, John D; Barros Aguirre, David; Ballell, Lluis; Besra, Gurdyal S; Argyrou, Argyrides

Batt, Sarah M; Cacho Izquierdo, Monica; Castro Pichel, Julia; Stubbs, Christopher J; Vela-Glez Del Peral, Laura; Pérez-Herrán, Esther; Dhar, Neeraj; Mouzon, Bernadette; Rees, Mike; Hutchinson, Jonathan P; Young, Robert J; McKinney, John D; Barros Aguirre, David; Ballell, Lluis; Besra, Gurdyal S; Argyrou, Argyrides.

Afiliação

Batt SM; School of Biosciences, University of Birmingham , Birmingham B15â¯2TT, United Kingdom.
Dhar N; School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL) , CH-1015 Lausanne, Switzerland.
McKinney JD; School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL) , CH-1015 Lausanne, Switzerland.
Besra GS; School of Biosciences, University of Birmingham , Birmingham B15â¯2TT, United Kingdom.

ACS Infect Dis ; 1(12): 615-26, 2015 Dec 11.

Article em En | MEDLINE | ID: mdl-27623058

Palavras-chave

drug discovery; multicopy suppression; target overexpression; time-lapse microscopy

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: ACS Infect Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido