From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells.

Chen, Jayson X; Wang, Hong; Liu, Anna; Zhang, Lanjing; Reuhl, Kenneth; Yang, Chung S

Chen, Jayson X; Wang, Hong; Liu, Anna; Zhang, Lanjing; Reuhl, Kenneth; Yang, Chung S.

Afiliação

Chen JX; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Wang H; Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Liu A; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Zhang L; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Reuhl K; Department of Pathology, University Medical Center of Princeton, Plainsboro, New Jersey.
Yang CS; Department of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey.

Toxicol Sci ; 155(1): 224-233, 2017 01.

Article em En | MEDLINE | ID: mdl-27664423

Assuntos

Neoplasias do Colo/induzido quimicamente; Sulfato de Dextrana/toxicidade; Imidazóis/toxicidade; Receptores Acoplados a Proteínas G/metabolismo; Animais; Linhagem Celular Tumoral; Neoplasias do Colo/enzimologia; Neoplasias do Colo/patologia; Feminino; Humanos; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

Colon carcinogenesis; DSS; Lgr5+; PhIP; ß-catenin

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Sulfato de Dextrana / Neoplasias do Colo / Receptores Acoplados a Proteínas G / Imidazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Toxicol Sci Assunto da revista: TOXICOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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