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Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Arts, Rob J W; Novakovic, Boris; Ter Horst, Rob; Carvalho, Agostinho; Bekkering, Siroon; Lachmandas, Ekta; Rodrigues, Fernando; Silvestre, Ricardo; Cheng, Shih-Chin; Wang, Shuang-Yin; Habibi, Ehsan; Gonçalves, Luís G; Mesquita, Inês; Cunha, Cristina; van Laarhoven, Arjan; van de Veerdonk, Frank L; Williams, David L; van der Meer, Jos W M; Logie, Colin; O'Neill, Luke A; Dinarello, Charles A; Riksen, Niels P; van Crevel, Reinout; Clish, Clary; Notebaart, Richard A; Joosten, Leo A B; Stunnenberg, Hendrik G; Xavier, Ramnik J; Netea, Mihai G.
Afiliação
  • Arts RJ; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands. Electronic address: rob.jw.arts@radboudumc.nl.
  • Novakovic B; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 HP Nijmegen, the Netherlands.
  • Ter Horst R; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Carvalho A; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • Bekkering S; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Lachmandas E; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Rodrigues F; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • Silvestre R; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • Cheng SC; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Institute of Molecular Medicine, National Tsing Hua University, 300 Hsinchu City, Taiwan.
  • Wang SY; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 HP Nijmegen, the Netherlands.
  • Habibi E; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 HP Nijmegen, the Netherlands.
  • Gonçalves LG; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal.
  • Mesquita I; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • Cunha C; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • van Laarhoven A; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • van de Veerdonk FL; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Williams DL; Department of Surgery, Quillen College of Medicine and Center for Inflammation, Infectious Disease and Immunity, East Tennessee State University, Johnson City, TN 37604, USA.
  • van der Meer JW; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Logie C; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 HP Nijmegen, the Netherlands.
  • O'Neill LA; Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland.
  • Dinarello CA; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.
  • Riksen NP; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • van Crevel R; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Clish C; Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Notebaart RA; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Joosten LA; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Stunnenberg HG; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 HP Nijmegen, the Netherlands.
  • Xavier RJ; Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology and Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Netea MG; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Cell Metab ; 24(6): 807-819, 2016 12 13.
Article em En | MEDLINE | ID: mdl-27866838

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Epigênese Genética / Fumaratos / Glutamina / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Metab Assunto da revista: METABOLISMO Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Epigênese Genética / Fumaratos / Glutamina / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Metab Assunto da revista: METABOLISMO Ano de publicação: 2016 Tipo de documento: Article