XTalkDB: a database of signaling pathway crosstalk.
Nucleic Acids Res
; 45(D1): D432-D439, 2017 01 04.
Article
em En
| MEDLINE
| ID: mdl-27899583
ABSTRACT
Analysis of signaling pathways and their crosstalk is a cornerstone of systems biology. Thousands of papers have been published on these topics. Surprisingly, there is no database that carefully and explicitly documents crosstalk between specific pairs of signaling pathways. We have developed XTalkDB (http//www.xtalkdb.org) to fill this very important gap. XTalkDB contains curated information for 650 pairs of pathways from over 1600 publications. In addition, the database reports the molecular components (e.g. proteins, hormones, microRNAs) that mediate crosstalk between a pair of pathways and the species and tissue in which the crosstalk was observed. The XTalkDB website provides an easy-to-use interface for scientists to browse crosstalk information by querying one or more pathways or molecules of interest.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Software
/
Transdução de Sinais
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Biologia Computacional
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Bases de Dados Genéticas
Idioma:
En
Revista:
Nucleic Acids Res
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos