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A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Carrasquillo, Minerva M; Allen, Mariet; Burgess, Jeremy D; Wang, Xue; Strickland, Samantha L; Aryal, Shivani; Siuda, Joanna; Kachadoorian, Michaela L; Medway, Christopher; Younkin, Curtis S; Nair, Asha; Wang, Chen; Chanana, Pritha; Serie, Daniel; Nguyen, Thuy; Lincoln, Sarah; Malphrus, Kimberly G; Morgan, Kevin; Golde, Todd E; Price, Nathan D; White, Charles C; De Jager, Philip L; Bennett, David A; Asmann, Yan W; Crook, Julia E; Petersen, Ronald C; Graff-Radford, Neill R; Dickson, Dennis W; Younkin, Steven G; Ertekin-Taner, Nilüfer.
Afiliação
  • Carrasquillo MM; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Allen M; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Burgess JD; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Wang X; Department of Health Sciences Research, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Strickland SL; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Aryal S; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Siuda J; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Kachadoorian ML; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Medway C; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA; Human Genetics Group, University of Nottingham, Nottingham, UK.
  • Younkin CS; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Nair A; Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA.
  • Wang C; Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA.
  • Chanana P; Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA.
  • Serie D; Department of Health Sciences Research, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Nguyen T; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Lincoln S; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Malphrus KG; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Morgan K; Human Genetics Group, University of Nottingham, Nottingham, UK.
  • Golde TE; Department of Neuroscience, University of Florida, Gainesville, FL, USA.
  • Price ND; Institute for Systems Biology, Seattle, WA, USA.
  • White CC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute, Camb
  • De Jager PL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute, Camb
  • Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Asmann YW; Department of Health Sciences Research, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Crook JE; Department of Health Sciences Research, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Petersen RC; Department of Neurology, Mayo Clinic Minnesota, Rochester, MN, USA.
  • Graff-Radford NR; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Dickson DW; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Younkin SG; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA.
  • Ertekin-Taner N; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA. Electronic address: taner.nilufer@mayo.edu.
Alzheimers Dement ; 13(6): 663-673, 2017 Jun.
Article em En | MEDLINE | ID: mdl-27939925
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Doença de Alzheimer Tipo de estudo: Etiology_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Alzheimers Dement Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Doença de Alzheimer Tipo de estudo: Etiology_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Alzheimers Dement Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos