White matter correlates of the disorganized speech dimension in schizophrenia.
Eur Arch Psychiatry Clin Neurosci
; 268(1): 99-104, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-28032254
ABSTRACT
Disorganized speech is related to functional abnormalities in schizophrenia. To test the association between formal thought disorders (FTDs) and white matter microstructure, we applied a behavioral rating and diffusion tensor imaging in 61 patients with schizophrenia spectrum disorders. The Bern Psychopathology Scale was used to rate the dimension of language abnormalities ranging from negative FTDs, basically unaltered speech, to positive FTDs. Tract-based spatial statistics indicated increased fractional anisotropy in left hemispheric pathways of the language system in patients with negative FTDs. Thus, altered white matter properties in relevant fiber tracts may represent vulnerability to specific formal thought disorders.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Esquizofrenia
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Distúrbios da Fala
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Estatística como Assunto
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Substância Branca
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur Arch Psychiatry Clin Neurosci
Assunto da revista:
NEUROLOGIA
/
PSIQUIATRIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Suíça