Comparative 3D micro-CT and 2D histomorphometry analysis of dental implant osseointegration in the maxilla of minipigs.
J Clin Periodontol
; 44(4): 418-427, 2017 Apr.
Article
em En
| MEDLINE
| ID: mdl-28063250
ABSTRACT
AIM:
The bone implant contact (BIC) has traditionally been evaluated with histological methods. Thereupon, strong correlations of two-dimensional (2D) BIC have been detected between µCT and destructive histology. However, due to the high intra-sample variability in BIC values, one histological slice is not sufficient to represent 3D BIC. Therefore, our aim has been to correlate the averaged values of 3-4 histological sections to 3D µCT. MATERIAL ANDMETHODS:
Fifty-four implants inserted into the maxilla of 14 minipigs were evaluated. Two different time points were selected to assess the 3D BIC (distance to implant 2-5 voxels), an inner ring (6-30 voxels) and an outer ring (55-100 voxels) using µCT (voxel size 10 µm) and to correlate the values to histomorphometry.RESULTS:
Strong correlations (p < 0.0001; 28 days, 56 days, total) were seen between µCT and histomorphometry concerning BIC (r = 0.84, r = 0.85, r = 0.83), the inner ring (r = 0.87, r = 0.87, r = 0.88) and the outer ring (r = 0.85, r = 0.85, r = 0.88). Closer to the implant, µCT values were higher compared with histomorphometry.CONCLUSION:
Although 3-4 histological slices per implant seem to predict the 3D BIC, µCT might be advantageous because of its non-destructive 3D character. The healing time may not impact on the comparability.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Implantes Dentários
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Osseointegração
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Imageamento Tridimensional
/
Microtomografia por Raio-X
/
Maxila
Limite:
Animals
Idioma:
En
Revista:
J Clin Periodontol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Alemanha