Adverse outcomes associated with postoperative atrial arrhythmias after lung transplantation: A meta-analysis and systematic review of the literature.
Clin Transplant
; 31(4)2017 04.
Article
em En
| MEDLINE
| ID: mdl-28181294
ABSTRACT
BACKGROUND:
Postoperative atrial arrhythmias (AAs) are common after lung transplantation, but studies are mixed regarding their impact on outcomes. We therefore performed this systematic review and meta-analysis to determine whether AAs after lung transplantation impede postoperative recovery.METHODS:
MEDLINE, EMBASE, CINAHL, and the Cochrane Register were searched to identify studies comparing outcomes in adult patients undergoing lung transplantation who experienced postoperative AAs in the immediate postoperative period vs those without postoperative AAs. Our primary outcome was perioperative mortality, and secondary outcomes were length of stay (LOS), postoperative complications, and mid-term (1-6 years) mortality.RESULTS:
Nine studies including 2653 patients were included in this analysis. Of this group, 791 (29.8%) had postoperative AAs. Patients with postoperative AAs had significantly higher perioperative (OR 2.70 [95% CI 1.73-4.19], P<.0001) mortality, longer hospital LOS (MD 8.29 [95% CI 4.37-12.21] days, P<.0001), more frequent requirement for tracheostomy (OR 4.67 [95% CI 2.59-8.44], P<.0001), and higher mid-term mortality (OR 1.71 [95% CI 1.28-2.30], P=.0003).CONCLUSIONS:
AAs after lung transplantation are frequent and associated with significantly higher mortality, longer hospital LOS, and requirement for tracheostomy. Given their impact on recovery, prophylactic strategies against AAs need to be developed.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
/
Complicações Pós-Operatórias
/
Transplante de Pulmão
/
Pneumopatias
Tipo de estudo:
Risk_factors_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Clin Transplant
Assunto da revista:
TRANSPLANTE
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos