Facial intramuscular lipoma occurrence following topical cosmetic injection with a mixture of basic fibroblast growth factor: A report of two cases.
J Cosmet Laser Ther
; 19(5): 303-306, 2017 Oct.
Article
em En
| MEDLINE
| ID: mdl-28296520
ABSTRACT
Growth factors and cytokines control cell growth, proliferation and differentiation via a network of inter- and intracellular signalling pathways, and are involved in skin self-renewing and wound healing. In recent years, topical and injectable growth factors and cytokines have emerged as an intriguing therapeutic modality that can be harnessed for aesthetic purposes. However, very little data are available on their long-term safety and tolerability. In this report, we describe two cases of patients, who developed intramuscular lipoma of the chin following topical injection with a mixture of basic fibroblast growth factor as the main ingredients for chin augmentation. Biopsies in the two cases were performed at our department, and revealed intramuscular lipoma. Our report indicates that the topical injection of growth factors can lead to tumorigenesis, so health care providers need to be aware of its potential consequences.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Faciais
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Fator 2 de Crescimento de Fibroblastos
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Neoplasias Musculares
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Lipoma
Limite:
Adult
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
J Cosmet Laser Ther
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article