Pulsed or continuous electromagnetic field induce p53/p21-mediated apoptotic signaling pathway in mouse spermatogenic cells in vitro and thus may affect male fertility.

Solek, Przemyslaw; Majchrowicz, Lena; Bloniarz, Dominika; Krotoszynska, Ewelina; Koziorowski, Marek

Solek, Przemyslaw; Majchrowicz, Lena; Bloniarz, Dominika; Krotoszynska, Ewelina; Koziorowski, Marek.

Afiliação

Solek P; Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland; Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland. Electronic address: pp.solek@gmail.com.
Majchrowicz L; Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland; Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland.
Bloniarz D; Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland; Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland.
Krotoszynska E; Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland; Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland.
Koziorowski M; Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland; Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland.

Toxicology ; 382: 84-92, 2017 05 01.

Article em En | MEDLINE | ID: mdl-28323003

Assuntos

Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Campos Eletromagnéticos/efeitos adversos; Fertilidade; Espermatócitos/fisiologia; Espermatogônias/fisiologia; Proteína Supressora de Tumor p53/metabolismo; Animais; Apoptose; Linhagem Celular; Fenômenos Fisiológicos Celulares; Masculino; Camundongos; Estresse Oxidativo; Transdução de Sinais

Palavras-chave

Apoptosis; Electromagnetic field; Fertility reduction; Mouse spermatogenic cells; P53/p21 pathway activation

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Espermatócitos / Espermatogônias / Proteína Supressora de Tumor p53 / Campos Eletromagnéticos / Inibidor de Quinase Dependente de Ciclina p21 / Fertilidade Limite: Animals Idioma: En Revista: Toxicology Ano de publicação: 2017 Tipo de documento: Article

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