Discomfort during bronchoscopy performed after endobronchial intubation with fentanyl and midazolam: a prospective study.
Jpn J Clin Oncol
; 47(5): 434-437, 2017 May 01.
Article
em En
| MEDLINE
| ID: mdl-28334767
ABSTRACT
OBJECTIVE:
Although endobronchial intubation during a bronchoscopic examination is useful for invasive procedures, it is not routine practice in Japan. The present study evaluated discomfort due to endobronchial intubation using fentanyl and midazolam sedation during bronchoscopy.METHODS:
Thirty-nine patients were enrolled prospectively from November 2014 to September 2015 at Okayama University Hospital. Fentanyl (20 µg) was administered to the patients just before endobronchial intubation, and fentanyl (10 µg) and midazolam (1 mg) were added as needed during the procedure. A questionnaire survey was administered 2 h after the examination. In the questionnaire, patient satisfaction was scored using a visual analog scale as follows excellent (1 point), good (2 points), normal (3 points), uncomfortable (4 points) and very uncomfortable (5 points). An additional question ('Do you remember the bronchoscopic examination?') was also asked. Predefined parameters (blood pressure, heart rate, oxygen saturation and complications) were recorded.RESULTS:
The enrolled patients included 22 males and 17 females; their median age was 70 (range 28-88) years. The patients received a mean dose of 47.9 µg of fentanyl (range 30-90 µg) and 2.79 mg of midazolam (range 1-7 mg). In total, 28 patients (71.7%) agreed to undergo a second bronchoscopic examination; the mean levels of discomfort and for the re-examination were 2.07 points each. About 41% of the patients remembered the bronchoscopic examination. No severe complications were reported.CONCLUSION:
Endobronchial intubation using fentanyl and midazolam sedation during an invasive bronchoscopic procedure might be recommended. CLINICAL TRIAL REGISTRATION UMIN000015578 in the UMIN Clinical Trials Registry.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Midazolam
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Broncoscopia
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Fentanila
/
Intubação
Tipo de estudo:
Clinical_trials
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Observational_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Jpn J Clin Oncol
Ano de publicação:
2017
Tipo de documento:
Article