Risk factors for low birth weight and preterm birth: A population-based case-control study in Wuhan, China.
J Huazhong Univ Sci Technolog Med Sci
; 37(2): 286-292, 2017 Apr.
Article
em En
| MEDLINE
| ID: mdl-28397036
ABSTRACT
Low birth weight (LBW) and preterm birth (PB) are associated with newborn mortality and diseases in adulthood. We explored factors related to LBW and PB by conducting a population-based case-control study from January 2011 to December 2013 in Wuhan, China. A total of 337 LBW newborn babies, 472 PB babies, and 708 babies with normal birth weights and born from term pregnancies were included in this study. Information of newborns and their parents was collected by trained investigators using questionnaires and referring to medical records. Univariate and logistic regression analyses with the stepwise selection method were used to determine the associations of related factors with LBW and PB. Results showed that maternal hypertension (OR=6.78, 95% CI 2.27-20.29, P=0.001), maternal high-risk pregnancy (OR=1.53, 95% CI 1.06-2.21, P=0.022), and maternal fruit intake ≥300 g per day during the first trimester (OR=1.70, 95% CI 1.17-2.45, P=0.005) were associated with LBW. BMI ≥24 kg/m2 of mother prior to delivery (OR=0.48, 95% CI 0.32-0.74, P=0.001) and gestation ≥37 weeks (OR=0.01, 95% CI 0.00-0.02, P<0.034) were protective factors for LBW. Maternal hypertension (OR=3.36, 95% CI 1.26-8.98, P=0.016), maternal high-risk pregnancy (OR=4.38, 95% CI 3.26-5.88, P<0.001), maternal meal intake of only twice per day (OR=1.88, 95% CI 1.10-3.20, P=0.021), and mother liking food with lots of aginomoto and salt (OR=1.60, 95% CI 1.02-2.51, P=0.040) were risk factors for PB. BMI ≥24 kg/m2 of mother prior to delivery (OR=0.66, 95% CI 0.47-0.93, P=0.018), distance of house from road ≥36 meters (OR=0.72, 95% CI 0.53-0.97, P=0.028), and living in rural area (OR= 0.60, 95% CI 0.37-0.99, P=0.047) were protective factors for PB. Our study demonstrated some risk factors and protective factors for LBW and PB, and provided valuable information for the prevention of the conditions among newborns.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Recém-Nascido de Baixo Peso
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Nascimento Prematuro
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Retardo do Crescimento Fetal
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Newborn
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Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Huazhong Univ Sci Technolog Med Sci
Assunto da revista:
MEDICINA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China