MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential.

Tigue, Natalie J; Bamber, Lisa; Andrews, John; Ireland, Samantha; Hair, James; Carter, Edward; Sridharan, Sudharsan; Jovanovic, Jelena; Rees, D Gareth; Springall, Jeremy S; Solier, Emilie; Li, Yi-Ming; Chodorge, Matthieu; Perez-Martinez, David; Higazi, Daniel R; Oberst, Michael; Kennedy, Maureen; Black, Chelsea M; Yan, Li; Schwickart, Martin; Maguire, Shaun; Cann, Jennifer A; de Haan, Lolke; Young, Lesley L; Vaughan, Tristan; Wilkinson, Robert W; Stewart, Ross

Tigue, Natalie J; Bamber, Lisa; Andrews, John; Ireland, Samantha; Hair, James; Carter, Edward; Sridharan, Sudharsan; Jovanovic, Jelena; Rees, D Gareth; Springall, Jeremy S; Solier, Emilie; Li, Yi-Ming; Chodorge, Matthieu; Perez-Martinez, David; Higazi, Daniel R; Oberst, Michael; Kennedy, Maureen; Black, Chelsea M; Yan, Li; Schwickart, Martin; Maguire, Shaun; Cann, Jennifer A; de Haan, Lolke; Young, Lesley L; Vaughan, Tristan; Wilkinson, Robert W; Stewart, Ross.

Afiliação

Tigue NJ; MedImmune Ltd , Cambridge, UK.
Bamber L; MedImmune Ltd , Cambridge, UK.
Andrews J; MedImmune Ltd , Cambridge, UK.
Ireland S; MedImmune Ltd , Cambridge, UK.
Hair J; MedImmune Ltd , Cambridge, UK.
Carter E; MedImmune Ltd , Cambridge, UK.
Sridharan S; MedImmune Ltd , Cambridge, UK.
Jovanovic J; MedImmune Ltd , Cambridge, UK.
Rees DG; MedImmune Ltd , Cambridge, UK.
Springall JS; MedImmune Ltd , Cambridge, UK.
Solier E; MedImmune Ltd , Cambridge, UK.
Li YM; MedImmune LLC , Gaithersburg, MD, USA.
Chodorge M; MedImmune Ltd , Cambridge, UK.
Perez-Martinez D; MedImmune Ltd , Cambridge, UK.
Higazi DR; MedImmune Ltd , Cambridge, UK.
Oberst M; MedImmune LLC , Gaithersburg, MD, USA.
Kennedy M; MedImmune LLC , Gaithersburg, MD, USA.
Black CM; MedImmune LLC , Gaithersburg, MD, USA.
Yan L; MedImmune LLC , Mountain View, CA, USA.
Schwickart M; MedImmune LLC , Mountain View, CA, USA.
Maguire S; MedImmune Ltd , Cambridge, UK.
Cann JA; MedImmune LLC , Gaithersburg, MD, USA.
de Haan L; MedImmune Ltd , Cambridge, UK.
Young LL; MedImmune Ltd , Cambridge, UK.
Vaughan T; MedImmune Ltd , Cambridge, UK.
Wilkinson RW; MedImmune Ltd , Cambridge, UK.
Stewart R; MedImmune Ltd , Cambridge, UK.

Oncoimmunology ; 6(3): e1280645, 2017.

Article em En | MEDLINE | ID: mdl-28405505

Palavras-chave

Agonist; GITR; GITRL; MEDI1873; T cell; hexamer; tumor

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Oncoimmunology Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido