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In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s.
Wang, Zhican; Fang, Ying; Teague, Juli; Wong, Hansen; Morisseau, Christophe; Hammock, Bruce D; Rock, Dan A; Wang, Zhengping.
Afiliação
  • Wang Z; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Fang Y; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Teague J; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Wong H; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Morisseau C; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Hammock BD; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Rock DA; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
  • Wang Z; Department of Pharmacokinetics and Drug Metabolism (Zhi.W., Y.F., D.A.R., Zhe.W.), and Clinical Pharmacology Modeling and Simulation (H.W.), Amgen Inc., South San Francisco, California; Drug Metabolism and Pharmacokinetics, Onyx Pharmaceuticals, an Amgen Subsidiary, South San Francisco, California (
Drug Metab Dispos ; 45(7): 712-720, 2017 07.
Article em En | MEDLINE | ID: mdl-28428366
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Clorpromazina / Sistema Enzimático do Citocromo P-450 / Epóxido Hidrolases / Inibidores de Proteassoma Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Clorpromazina / Sistema Enzimático do Citocromo P-450 / Epóxido Hidrolases / Inibidores de Proteassoma Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article