Anthropometric measures are not accurate predictors of fat mass in ALS.
Amyotroph Lateral Scler Frontotemporal Degener
; 18(7-8): 486-491, 2017 11.
Article
em En
| MEDLINE
| ID: mdl-28446030
ABSTRACT
BACKGROUND:
Anthropometric measurements including body mass index (BMI) and body adiposity index (BAI) are widely employed as indicators of fat mass (FM). Metabolic abnormalities in amyotrophic lateral sclerosis (ALS) impact disease progression, therefore assessment of FM informs care. The aim of this study was to determine whether BMI and BAI are accurate predictors of FM in ALS. Methodology and mainfindings:
BMI, BAI and percentage FM (determined by air displacement plethysmography; FM-ADP) were measured in control (n = 35) and ALS (n = 44) participants. While BMI and BAI correlated significantly with FM-ADP, neither index provided an accurate estimate of FM. In longitudinally assessed ALS participants (n = 29; â¼six-month repeat assessment interval), although a change in BMI (r2 = 0.62 r = 0.79 p < 0.01) and BAI (r2 = 0.20 r = 0.44, p = 0.02) correlated with a change in FM-ADP, the anthropometric measures did not consistently reflect increases or decreases observed in FM-ADP. CONCLUSIONS/SIGNIFICANCE:
Using FM-ADP as the standard, this study suggests that BMI and BAI are not accurate measures of FM in ALS. Furthermore, longitudinal assessments indicate that changes in BMI and BAI do not consistently reflect true changes of FM in ALS.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Pletismografia de Impedância
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Índice de Massa Corporal
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Antropometria
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Adiposidade
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Esclerose Lateral Amiotrófica
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Amyotroph Lateral Scler Frontotemporal Degener
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Austrália