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Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
Kline, Cassie N; Joseph, Nancy M; Grenert, James P; van Ziffle, Jessica; Talevich, Eric; Onodera, Courtney; Aboian, Mariam; Cha, Soonmee; Raleigh, David R; Braunstein, Steve; Torkildson, Joseph; Samuel, David; Bloomer, Michelle; Campomanes, Alejandra G de Alba; Banerjee, Anuradha; Butowski, Nicholas; Raffel, Corey; Tihan, Tarik; Bollen, Andrew W; Phillips, Joanna J; Korn, W Michael; Yeh, Iwei; Bastian, Boris C; Gupta, Nalin; Mueller, Sabine; Perry, Arie; Nicolaides, Theodore; Solomon, David A.
Afiliação
  • Kline CN; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California San Francisco (UCSF), San Francisco, California, USA.
  • Joseph NM; Department of Pathology, UCSF, San Francisco, California, USA.
  • Grenert JP; Clinical Cancer Genomics Laboratory, UCSF, San Francisco, California, USA.
  • van Ziffle J; Department of Pathology, UCSF, San Francisco, California, USA.
  • Talevich E; Clinical Cancer Genomics Laboratory, UCSF, San Francisco, California, USA.
  • Onodera C; Department of Pathology, UCSF, San Francisco, California, USA.
  • Aboian M; Clinical Cancer Genomics Laboratory, UCSF, San Francisco, California, USA.
  • Cha S; Clinical Cancer Genomics Laboratory, UCSF, San Francisco, California, USA.
  • Raleigh DR; Clinical Cancer Genomics Laboratory, UCSF, San Francisco, California, USA.
  • Braunstein S; Department of Radiology, UCSF, San Francisco, California, USA.
  • Torkildson J; Department of Radiology, UCSF, San Francisco, California, USA.
  • Samuel D; Department of Neurological Surgery, UCSF, San Francisco, California, USA.
  • Bloomer M; Department of Radiation Oncology, UCSF, San Francisco, California, USA.
  • Campomanes AGA; Department of Radiation Oncology, UCSF, San Francisco, California, USA.
  • Banerjee A; Division of Pediatric Hematology/Oncology, UCSF Benioff Children's Hospital Oakland,Oakland, California, USA.
  • Butowski N; Division of Pediatric Hematology/Oncology, Valley Children's Hospital, Madera, California, USA.
  • Raffel C; Department of Ophthalmology, UCSF, San Francisco, California, USA.
  • Tihan T; Department of Ophthalmology, UCSF, San Francisco, California, USA.
  • Bollen AW; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California San Francisco (UCSF), San Francisco, California, USA.
  • Phillips JJ; Department of Neurological Surgery, UCSF, San Francisco, California, USA.
  • Korn WM; Division of Neuro-Oncology, Department of Neurological Surgery, UCSF, San Francisco, California, USA.
  • Yeh I; Department of Neurological Surgery, UCSF, San Francisco, California, USA.
  • Bastian BC; Department of Pathology, UCSF, San Francisco, California, USA.
  • Gupta N; Department of Pathology, UCSF, San Francisco, California, USA.
  • Mueller S; Department of Pathology, UCSF, San Francisco, California, USA.
  • Perry A; Department of Neurological Surgery, UCSF, San Francisco, California, USA.
  • Nicolaides T; Divisions of Gastroenterology and Medical Oncology, Department of Medicine, UCSF, San Francisco, California, USA.
  • Solomon DA; Department of Pathology, UCSF, San Francisco, California, USA.
Neuro Oncol ; 19(5): 699-709, 2017 05 01.
Article em En | MEDLINE | ID: mdl-28453743
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Biomarcadores Tumorais / Mutação em Linhagem Germinativa / Terapia de Alvo Molecular / Sequenciamento de Nucleotídeos em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Neuro Oncol Assunto da revista: NEOPLASIAS / NEUROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Biomarcadores Tumorais / Mutação em Linhagem Germinativa / Terapia de Alvo Molecular / Sequenciamento de Nucleotídeos em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Neuro Oncol Assunto da revista: NEOPLASIAS / NEUROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos