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Pyrimethamine significantly lowers cerebrospinal fluid Cu/Zn superoxide dismutase in amyotrophic lateral sclerosis patients with SOD1 mutations.
Lange, Dale J; Shahbazi, Mona; Silani, Vincenzo; Ludolph, Albert C; Weishaupt, Jochen H; Ajroud-Driss, Senda; Fields, Kara G; Remanan, Rahul; Appel, Stanley H; Morelli, Claudia; Doretti, Alberto; Maderna, Luca; Messina, Stefano; Weiland, Ulrike; Marklund, Stefan L; Andersen, Peter M.
Afiliação
  • Lange DJ; Department of Neurology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY.
  • Shahbazi M; Department of Neurology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY.
  • Silani V; Department of Neurology and Laboratory Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Italian Auxological Institute, Milan, Italy.
  • Ludolph AC; Department of Pathophysiology and Transplantation, Dino Ferrari Center, University of Milan, Milan, Italy.
  • Weishaupt JH; Department of Neurology, Ulm University, Ulm, Germany.
  • Ajroud-Driss S; Department of Neurology, Ulm University, Ulm, Germany.
  • Fields KG; Department of Neurology, Northwestern University, Chicago, IL.
  • Remanan R; Hospital for Special Surgery Healthcare Research Institute, New York, NY.
  • Appel SH; Department of Neurology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY.
  • Morelli C; Methodist Hospital, Weill Cornell Medicine, Houston, TX.
  • Doretti A; Department of Neurology and Laboratory Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Italian Auxological Institute, Milan, Italy.
  • Maderna L; Department of Neurology and Laboratory Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Italian Auxological Institute, Milan, Italy.
  • Messina S; Department of Neurology and Laboratory Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Italian Auxological Institute, Milan, Italy.
  • Weiland U; Department of Neurology and Laboratory Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Italian Auxological Institute, Milan, Italy.
  • Marklund SL; Department of Neurology, Ulm University, Ulm, Germany.
  • Andersen PM; Departments of Medical Biosciences.
Ann Neurol ; 81(6): 837-848, 2017 Jun.
Article em En | MEDLINE | ID: mdl-28480639
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirimetamina / Índice de Gravidade de Doença / Antagonistas do Ácido Fólico / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Neurol Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirimetamina / Índice de Gravidade de Doença / Antagonistas do Ácido Fólico / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Neurol Ano de publicação: 2017 Tipo de documento: Article