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Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level.
Sasatani, Megumi; Xi, Yang; Kajimura, Junko; Kawamura, Toshiyuki; Piao, Jinlian; Masuda, Yuji; Honda, Hiroaki; Kubo, Kei; Mikamoto, Takahiro; Watanabe, Hiromitsu; Xu, Yanbin; Kawai, Hidehiko; Shimura, Tsutomu; Noda, Asao; Hamasaki, Kanya; Kusunoki, Yoichiro; Zaharieva, Elena Karamfilova; Kamiya, Kenji.
Afiliação
  • Sasatani M; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Xi Y; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Kajimura J; Diabetes Center, Zhejiang Provincial Key Laboratory of Pathophysiology, Institute of Biochemistry and Molecular Biology, School of Medicine, Ningbo University, Ningbo 315211, China.
  • Kawamura T; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Piao J; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima 732-0815, Japan.
  • Masuda Y; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Honda H; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Kubo K; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Mikamoto T; Department of Genome Dynamics, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.
  • Watanabe H; Department of Toxicogenomics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
  • Xu Y; Department of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Kawai H; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Shimura T; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Noda A; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Hamasaki K; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Kusunoki Y; Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.
  • Zaharieva EK; Department of Environmental Health, National Institute of Public Health, 2-3-6, Minami, Wako, Saitama 351-0197, Japan and.
  • Kamiya K; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima 732-0815, Japan.
Carcinogenesis ; 38(5): 570-578, 2017 05 01.
Article em En | MEDLINE | ID: mdl-28498946
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Carcinógenos / Adenoma / Expressão Gênica / Mutação Puntual / Apoptose / Neoplasias Intestinais / Nucleotidiltransferases Limite: Animals Idioma: En Revista: Carcinogenesis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Carcinógenos / Adenoma / Expressão Gênica / Mutação Puntual / Apoptose / Neoplasias Intestinais / Nucleotidiltransferases Limite: Animals Idioma: En Revista: Carcinogenesis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão