Athero-inflammatory nanotherapeutics: Ferulic acid-based poly(anhydride-ester) nanoparticles attenuate foam cell formation by regulating macrophage lipogenesis and reactive oxygen species generation.

Chmielowski, Rebecca A; Abdelhamid, Dalia S; Faig, Jonathan J; Petersen, Latrisha K; Gardner, Carol R; Uhrich, Kathryn E; Joseph, Laurie B; Moghe, Prabhas V

Chmielowski, Rebecca A; Abdelhamid, Dalia S; Faig, Jonathan J; Petersen, Latrisha K; Gardner, Carol R; Uhrich, Kathryn E; Joseph, Laurie B; Moghe, Prabhas V.

Afiliação

Chmielowski RA; Department of Chemical and Biochemical Engineering, 98 Brett Rd, Rutgers University, NJ, USA.
Abdelhamid DS; Department of Chemistry and Chemical Biology, 610 Taylor Rd., Rutgers University, NJ, USA; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minya, Egypt.
Faig JJ; Department of Chemistry and Chemical Biology, 610 Taylor Rd., Rutgers University, NJ, USA.
Petersen LK; Department of Biomedical Engineering, 599 Taylor Rd., Rutgers University, NJ, USA.
Gardner CR; Department of Pharmacology and Toxicology, 160 Frelinghuysen Road, Rutgers University, NJ, USA.
Uhrich KE; Department of Chemistry and Chemical Biology, 610 Taylor Rd., Rutgers University, NJ, USA.
Joseph LB; Department of Pharmacology and Toxicology, 160 Frelinghuysen Road, Rutgers University, NJ, USA. Electronic address: lbjoseph@pharmacy.rutgers.edu.
Moghe PV; Department of Chemical and Biochemical Engineering, 98 Brett Rd, Rutgers University, NJ, USA; Department of Biomedical Engineering, 599 Taylor Rd., Rutgers University, NJ, USA. Electronic address: moghe@rutgers.edu.

Acta Biomater ; 57: 85-94, 2017 07 15.

Article em En | MEDLINE | ID: mdl-28522412

Assuntos

Anti-Inflamatórios; Aterosclerose; Ácidos Cumáricos; Células Espumosas/metabolismo; Lipogênese/efeitos dos fármacos; Nanopartículas; Polianidridos; Espécies Reativas de Oxigênio/metabolismo; Anti-Inflamatórios/farmacologia; Aterosclerose/tratamento farmacológico; Aterosclerose/metabolismo; Aterosclerose/patologia; Ácidos Cumáricos/química; Ácidos Cumáricos/farmacologia; Células Espumosas/patologia; Humanos; Nanopartículas/química; Nanopartículas/uso terapêutico; Polianidridos/química; Polianidridos/farmacologia

Palavras-chave

Atherosclerosis; Ferulic acid; Nanomedicine; Oxidized low density; Scavenger receptors

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / Ácidos Cumáricos / Polianidridos / Aterosclerose / Lipogênese / Nanopartículas / Células Espumosas / Anti-Inflamatórios Limite: Humans Idioma: En Revista: Acta Biomater Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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