Lichenoid Drug Eruption with Prominent Nail Changes Due to Leflunomide in a 12-Year-Old Child.
Pediatr Dermatol
; 34(4): e225-e226, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28543792
ABSTRACT
We present the case of a 12-year-old-girl who developed lichenoid dermatitis approximately 1 year after starting leflunomide for juvenile idiopathic arthritis. The eruption resolved promptly with discontinuation of the suspected culprit agent, supportive of a lichenoid drug eruption, but she subsequently developed markedly dystrophic nails with lichen planus-like features. A biopsy of her cutaneous findings at the time of initial presentation demonstrated lichenoid dermatitis, and a nail matrix biopsy was deferred given clinical correlation. Prominent nail changes in lichenoid drug eruptions, particularly in children, are rare but should be considered in children with new-onset nail dystrophy.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Erupções Liquenoides
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Toxidermias
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Antirreumáticos
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Isoxazóis
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Doenças da Unha
Limite:
Child
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Female
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Humans
Idioma:
En
Revista:
Pediatr Dermatol
Ano de publicação:
2017
Tipo de documento:
Article