Neurodevelopmental outcome of isolated ventriculomegaly: a prospective cohort study.
Prenat Diagn
; 37(8): 764-768, 2017 Aug.
Article
em En
| MEDLINE
| ID: mdl-28568219
ABSTRACT
OBJECTIVE:
Data regarding the neurodevelopmental outcome of children diagnosed in utero with isolated ventriculomegaly (IVM) are limited and principally founded on ultrasound-based studies. Here, we endeavored to assess the outcome of such cases in a large-scale, magnetic resonance imaging (MRI)-based study.METHODS:
We conducted a study on 133 cases of IVM with a documented fetal brain MRI scan. Children were assessed at ages 18 to 36 months by using the Vineland Adaptive Behavior Scales (VABS).RESULTS:
Vineland Adaptive Behavior Scales scores were within normal range. There was no significant difference between VABS score in symmetric versus asymmetric IVM (101.7 vs. 101.6, respectively; p = 0.94), and the VABS score of mild IVM was comparable with that of moderate IVM (101.8 vs. 101; p = 0.8). Only five cases (3.8%) were found to have an abnormal score (<85). There was no significant difference in the rate of abnormal scores between mild and moderate IVM (2.8% vs. 8.3%, respectively; p = 0.22).CONCLUSION:
In cases of isolated ventriculomegaly, a normal neurodevelopmental outcome is to be expected; moreover, the outcome does not appear to be affected by the severity or asymmetry of the ventriculomegaly. Thus, following a meticulous workup, patients can be given reassuring counseling regarding the child's prognosis. © 2017 John Wiley & Sons, Ltd.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Desenvolvimento Infantil
/
Hidrocefalia
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Child, preschool
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Humans
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Infant
País/Região como assunto:
Asia
Idioma:
En
Revista:
Prenat Diagn
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Israel