Prevalence of hearing-loss among HAART-treated children in the Horn of Africa.
Int J Pediatr Otorhinolaryngol
; 98: 166-170, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28583495
ABSTRACT
OBJECTIVES:
The prevalence of hearing loss (HL) in children infected with HIV/AIDS is not well studied. Even fewer studies focus on stable HIV-infected children treated with high-effective antiretroviral therapy (HAART). We aim to compare the prevalence of ear disease and HL in HAART-treated, HIV + children in Addis Ababa, Ethiopia with a well, similarly-aged elementary school population with unknown HIV status (HIVU).METHODS:
Children underwent standard head and neck examination and cerumen removal by board certified otolaryngologists. Next, certified audiologists performed hearing screening with pure-tone audiometry using a circumaural headset but without an ambient noise reducing environment. Children failing audiometric screening underwent full behavioral audiometry including air and bone testing. The primary outcome parameter was HL > 25 dB with the audiologist accounting for background noise. A second endpoint was PTA >40 dB (500, 1000, 2000 Hz) without assessment of background noise.RESULTS:
107 HIV+ and 147 HIVU children met inclusion criteria. In the HIV + cohort 17.8% had evidence of TM perforations and 8.4% had otorrhea. In the HIVU group 2.7% had a TM perforation and 0% had otorrhea. Hearing was significantly worse in HIV + children. (Audiologist determination 38.3% HL HIV+, 12.2% HIVU, Fisher's-Exact-Test OR 4.5, 95% CI 2.4-8.3, p-value <0.0001; Worse-hearing-ear PTA > 40 dB 19.6% HL HIV+, 6.1% HIVU, OR 3.7, 95% CI 1.7-8.4, p-value <0.001).CONCLUSIONS:
Chronic OM, conductive and mixed hearing losses are significantly more common in HAART-treated HIV + children than in well, similarly-aged controls. Rates of SNHL are similar.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Terapia Antirretroviral de Alta Atividade
/
Otopatias
/
Perda Auditiva
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
Int J Pediatr Otorhinolaryngol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos