Achieving a satisfactory clinical and biochemical response in antiphospholipid syndrome and severe thrombocytopenia with rituximab: two case reports.
Clin Case Rep
; 5(6): 845-848, 2017 06.
Article
em En
| MEDLINE
| ID: mdl-28588823
ABSTRACT
In AP syndrome (APS) with severe thrombocytopenia, rituximab represents a unique drug which can balance the effect of bleeding and thrombosis. By reducing the production of autoantibodies, rituximab can simultaneously raise the platelets and reduce the chance of thrombosis by suppressing APL antibodies. Rituximab can supersede splenectomy as second-line therapy in similar patients.
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MEDLINE
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En
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Clin Case Rep
Ano de publicação:
2017
Tipo de documento:
Article