DRESS Syndrome or Hematologic Malignancy?: A Case Report of a 4-Year-Old Boy.
Pediatr Emerg Care
; 33(7): 494-496, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28665895
ABSTRACT
Drug reaction with eosinophilia and systemic symptom (DRESS) is a serious idiosyncratic drug reaction. It is characterized by skin eruption, fever, hematologic abnormalities, and multi-organ involvement. Diagnosis is challenging because of the wide clinical spectrum. Its association with aromatic antiepileptic drugs, such as phenytoin, phenobarbital, and carbamazepine, has been well described in adults. There are few reports of DRESS syndrome in children, and knowledge about the relationship between new antiepileptic drugs such as oxcarbazepine and this syndrome is limited. The DRESS syndrome is a challenging entity and probably underdiagnosed because many of its clinical findings can mimic those of other serious systemic disorders such as infections and hematologic disorders. Virus reactivation and use of some drugs together with suspected drugs, such as amoxicillin, can trigger the symptoms of DRESS syndrome. This is a case report of a 4-year-old boy with oxcarbazepine-induced DRESS syndrome possibly triggered by amoxicillin; hematologic malignancy was included in the differential diagnosis.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Carbamazepina
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Neoplasias Hematológicas
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Síndrome de Hipersensibilidade a Medicamentos
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Amoxicilina
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Antibacterianos
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Anticonvulsivantes
Tipo de estudo:
Diagnostic_studies
Limite:
Child, preschool
/
Humans
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Male
Idioma:
En
Revista:
Pediatr Emerg Care
Assunto da revista:
MEDICINA DE EMERGENCIA
/
PEDIATRIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Turquia