Migraine and percutaneous patent foramen ovale closure: a systematic review and meta-analysis.
BMC Cardiovasc Disord
; 17(1): 203, 2017 07 26.
Article
em En
| MEDLINE
| ID: mdl-28747203
ABSTRACT
BACKGROUND:
The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. However, the benefits of PFO closure are less certain in patients with migraine without aura (MwoA).METHODS:
We systematically searched Pubmed for pertinent clinical studies published from January 2000 to July 2015. The primary end-point was the elimination or significant improvement of migraine symptoms after PFO closure.RESULTS:
Upon screening an initial list of 315 publications, we identified eight studies that included 546 patients. Overall, our analysis indicated a significant improvement of migraine in 81% of MA cases compared to only 63% of MwoA cases. The summary odds ratio was 2.5 (95% confidence interval 1.09-5.73), and the benefits of PFO closure were significantly greater for patients with MA compared to patients with MwoA (P = 0.03).CONCLUSIONS:
The presence of aura provides a reference standard for the clinical selection of patients with migraine for PFO closure intervention.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Cateterismo Cardíaco
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Enxaqueca com Aura
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Enxaqueca sem Aura
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Forame Oval Patente
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
BMC Cardiovasc Disord
Assunto da revista:
ANGIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China