Cocrystal formation, crystal structure, solubility and permeability studies for novel 1,2,4-thiadiazole derivative as a potent neuroprotector.

Surov, Artem O; Volkova, Tatyana V; Churakov, Andrei V; Proshin, Alexey N; Terekhova, Irina V; Perlovich, German L

Surov, Artem O; Volkova, Tatyana V; Churakov, Andrei V; Proshin, Alexey N; Terekhova, Irina V; Perlovich, German L.

Afiliação

Surov AO; Institution of Russian Academy of Sciences, G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia.
Volkova TV; Institution of Russian Academy of Sciences, G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia.
Churakov AV; Institute of General and Inorganic Chemistry RAS, Leninsky Prosp. 31, 119991 Moscow, Russia.
Proshin AN; Institute of Physiologically Active Compounds of Russian Academy of Sciences, 142432 Chernogolovka, Russia.
Terekhova IV; Institution of Russian Academy of Sciences, G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia.
Perlovich GL; Institution of Russian Academy of Sciences, G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia. Electronic address: glp@isc-ras.ru.

Eur J Pharm Sci ; 109: 31-39, 2017 Nov 15.

Article em En | MEDLINE | ID: mdl-28756204

Assuntos

Fármacos Neuroprotetores/química; Tiadiazóis/química; Celulose/química; Cristalização; Permeabilidade; Solubilidade; Ácido Vanílico/química

Palavras-chave

1,2,4-Thiadiazole; Cocrystal; Formation thermodynamics; Permeability; Solubility

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tiadiazóis / Fármacos Neuroprotetores Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Federação Russa

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