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Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.
Arduino, Daniela M; Wettmarshausen, Jennifer; Vais, Horia; Navas-Navarro, Paloma; Cheng, Yiming; Leimpek, Anja; Ma, Zhongming; Delrio-Lorenzo, Alba; Giordano, Andrea; Garcia-Perez, Cecilia; Médard, Guillaume; Kuster, Bernhard; García-Sancho, Javier; Mokranjac, Dejana; Foskett, J Kevin; Alonso, M Teresa; Perocchi, Fabiana.
Afiliação
  • Arduino DM; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Wettmarshausen J; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Vais H; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Navas-Navarro P; Instituto de Biología y Genética Molecular (IBGM), University of Valladolid and Consejo Superior de Investigaciones Científicas (CSIC), Valladolid 47003, Spain.
  • Cheng Y; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Leimpek A; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Ma Z; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Delrio-Lorenzo A; Instituto de Biología y Genética Molecular (IBGM), University of Valladolid and Consejo Superior de Investigaciones Científicas (CSIC), Valladolid 47003, Spain.
  • Giordano A; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Garcia-Perez C; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Médard G; Chair for Proteomics and Bioanalytics, Technical University Munich, Freising 85354, Germany.
  • Kuster B; Chair for Proteomics and Bioanalytics, Technical University Munich, Freising 85354, Germany; Center for Integrated Protein Science Munich, Freising 85354, Germany.
  • García-Sancho J; Instituto de Biología y Genética Molecular (IBGM), University of Valladolid and Consejo Superior de Investigaciones Científicas (CSIC), Valladolid 47003, Spain.
  • Mokranjac D; Biomedical Center, Department of Physiological Chemistry, Ludwig-Maximilians Universität München, Martinsried 81377, Germany.
  • Foskett JK; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Alonso MT; Instituto de Biología y Genética Molecular (IBGM), University of Valladolid and Consejo Superior de Investigaciones Científicas (CSIC), Valladolid 47003, Spain.
  • Perocchi F; Gene Center/Department of Biochemistry, Ludwig-Maximilians Universität München, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg 85764, Germany. Electronic address: perocchi@genzentrum.lmu.de.
Mol Cell ; 67(4): 711-723.e7, 2017 Aug 17.
Article em En | MEDLINE | ID: mdl-28820965
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Bloqueadores dos Canais de Cálcio / Canais de Cálcio / Cálcio / Mitoxantrona / Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Mitocôndrias Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Bloqueadores dos Canais de Cálcio / Canais de Cálcio / Cálcio / Mitoxantrona / Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Mitocôndrias Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha