Characterization of the Asian Phenotype - An Emerging Paradigm with Clinicopathological and Human Research Implications.
Int J Med Sci
; 14(7): 639-647, 2017.
Article
em En
| MEDLINE
| ID: mdl-28824295
ABSTRACT
Background:
Modern medicine recognizes that salient, inherent variations between Caucasians and Asians exist. Radical changes are occurring in the health scene with increasing emphasis centered on the recognition of inter-individual variations unique to Asians that impact on medical management and outcomes.Aim:
This review analyzes distinct features or outcomes in terms of epidemiology, disease thresholds, diagnostic cutoffs and treatment responses of Asian people compared with non-Asians.Methods:
This review is based on a literature search via PubMed and MEDLINE for relevant articles related to the Asian phenotype and its impact on health and disease.Results:
An 'Asian phenotype' could be characterized across the spectrum of biomedical disciplines and underscores the major challenges clinicians must face in their daily management of a cosmopolitan population and their extrapolation of research outcomes.Conclusion:
Interventions for various ailments that have traditionally ignored population differences have now entered the age of personalized, stratified or precision medicine requiring an individualized approach being adopted as a new standard of care. Factoring in Asian phenotypes is essential for the medical research community and the development of improved clinical practice guidelines across a continuum of disciplines that will ultimately translate to better human health round the world.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Epidemiologia Molecular
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Povo Asiático
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População Branca
Tipo de estudo:
Guideline
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Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Int J Med Sci
Assunto da revista:
MEDICINA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Singapura