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Effect of CYP3A4*22, CYP3A5*3, and CYP3A combined genotypes on tamoxifen metabolism.
Sanchez Spitman, A B; Moes, D J A R; Gelderblom, H; Dezentje, V O; Swen, J J; Guchelaar, H J.
Afiliação
  • Sanchez Spitman AB; Leiden Network for Personalised Therapeutics, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2300, RC, The Netherlands.
  • Moes DJAR; Leiden Network for Personalised Therapeutics, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2300, RC, The Netherlands.
  • Gelderblom H; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
  • Dezentje VO; Department of Medical Oncology, Reinier de Graaf, Delft, The Netherlands.
  • Swen JJ; Leiden Network for Personalised Therapeutics, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2300, RC, The Netherlands.
  • Guchelaar HJ; Leiden Network for Personalised Therapeutics, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2300, RC, The Netherlands. h.j.guchelaar@lumc.nl.
Eur J Clin Pharmacol ; 73(12): 1589-1598, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28849250

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tamoxifeno / Antineoplásicos Hormonais / Citocromo P-450 CYP3A / Genótipo / Isoenzimas Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Eur J Clin Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tamoxifeno / Antineoplásicos Hormonais / Citocromo P-450 CYP3A / Genótipo / Isoenzimas Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Eur J Clin Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda