Sex and Circadian Periodicity of Cardiovascular Diseases: Are Women Sufficiently Represented in Chronobiological Studies?
Heart Fail Clin
; 13(4): 719-738, 2017 Oct.
Article
em En
| MEDLINE
| ID: mdl-28865781
ABSTRACT
Women are often excluded/underrepresented in clinical trials; sometimes, the number of men/women participants or separate analysis by sex are not reported. A robust body of evidence demonstrated that several life-threatening acute cardiovascular diseases, for example, acute myocardial infarction, sudden cardiac death, cardiac arrest, rupture or dissection of aortic aneurysms, and stroke, exhibit a circadian periodicity with a morning peak. An analysis of 20 years of chronobiologic studies (44% of them, accounting for 85% of total cases, with separate analysis by sex) confirmed that morning hours are a critical time of onset of acute cardiovascular diseases in men and women.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
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Ritmo Circadiano
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
Heart Fail Clin
Ano de publicação:
2017
Tipo de documento:
Article