The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline.

Paragas, Erickson M; Humphreys, Sara C; Min, Joshua; Joswig-Jones, Carolyn A; Jones, Jeffrey P

Paragas, Erickson M; Humphreys, Sara C; Min, Joshua; Joswig-Jones, Carolyn A; Jones, Jeffrey P.

Afiliação

Paragas EM; Department of Chemistry, Washington State University, Pullman, WA 99164, United States.
Humphreys SC; Department of Chemistry, Washington State University, Pullman, WA 99164, United States.
Min J; Department of Chemistry, Washington State University, Pullman, WA 99164, United States.
Joswig-Jones CA; Department of Chemistry, Washington State University, Pullman, WA 99164, United States.
Jones JP; Department of Chemistry, Washington State University, Pullman, WA 99164, United States. Electronic address: jpj@wsu.edu.

Biochem Pharmacol ; 145: 210-217, 2017 12 01.

Article em En | MEDLINE | ID: mdl-28888950

Assuntos

Aldeído Oxidase/metabolismo; Nitroquinolinas/metabolismo; Aldeído Oxidase/antagonistas & inibidores; Aldeído Oxidase/genética; Anti-Hipertensivos/farmacologia; Domínio Catalítico; Escherichia coli; Humanos; Hidralazina/farmacologia; Cinética; Estrutura Molecular; Nitroquinolinas/química; Oxirredução

Palavras-chave

Aldehyde oxidase; Drug metabolism; Molybdenum; Nitric oxide; Oxidation; Reactive-oxygen; Reduction

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Aldeído Oxidase / Nitroquinolinas Limite: Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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