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A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Peters, Lauren A; Perrigoue, Jacqueline; Mortha, Arthur; Iuga, Alina; Song, Won-Min; Neiman, Eric M; Llewellyn, Sean R; Di Narzo, Antonio; Kidd, Brian A; Telesco, Shannon E; Zhao, Yongzhong; Stojmirovic, Aleksandar; Sendecki, Jocelyn; Shameer, Khader; Miotto, Riccardo; Losic, Bojan; Shah, Hardik; Lee, Eunjee; Wang, Minghui; Faith, Jeremiah J; Kasarskis, Andrew; Brodmerkel, Carrie; Curran, Mark; Das, Anuk; Friedman, Joshua R; Fukui, Yoshinori; Humphrey, Mary Beth; Iritani, Brian M; Sibinga, Nicholas; Tarrant, Teresa K; Argmann, Carmen; Hao, Ke; Roussos, Panos; Zhu, Jun; Zhang, Bin; Dobrin, Radu; Mayer, Lloyd F; Schadt, Eric E.
Afiliação
  • Peters LA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Perrigoue J; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Mortha A; Sema4, a Mount Sinai venture, Stamford, Connecticut, USA.
  • Iuga A; Janssen Research and Development, LLC., Spring House, Pennsylvania, USA.
  • Song WM; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
  • Neiman EM; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Llewellyn SR; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.
  • Di Narzo A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kidd BA; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Telesco SE; Janssen Research and Development, LLC., Spring House, Pennsylvania, USA.
  • Zhao Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Stojmirovic A; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Sendecki J; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Shameer K; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Miotto R; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Losic B; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Shah H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Lee E; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Wang M; Janssen Research and Development, LLC., Spring House, Pennsylvania, USA.
  • Faith JJ; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kasarskis A; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Brodmerkel C; Janssen Research and Development, LLC., Spring House, Pennsylvania, USA.
  • Curran M; Janssen Research and Development, LLC., Spring House, Pennsylvania, USA.
  • Das A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Friedman JR; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Fukui Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Humphrey MB; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Iritani BM; Institute for Next-Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Sibinga N; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Tarrant TK; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Argmann C; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Roussos P; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Zhu J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Zhang B; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Dobrin R; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Mayer LF; Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Schadt EE; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nat Genet ; 49(10): 1437-1449, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28892060

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Genes Reguladores / Genômica / Redes Reguladoras de Genes / Modelos Genéticos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Genes Reguladores / Genômica / Redes Reguladoras de Genes / Modelos Genéticos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos