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Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer.
Rai, Amit; Kumar, Umesh; Raj, Vinit; Singh, Ashok K; Kumar, Pranesh; Keshari, Amit K; Kumar, Dinesh; Maity, Biswanath; De, Arnab; Samanta, Amalesh; Nath, Sneha; Prakash, Anand; Gosipatala, Sunil Babu; Chand, Gyan; Saha, Sudipta.
Afiliação
  • Rai A; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Kumar U; Centre of Biomedical Research, SGPGIMS Campus, Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
  • Raj V; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Singh AK; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Kumar P; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Keshari AK; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Kumar D; Centre of Biomedical Research, SGPGIMS Campus, Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
  • Maity B; Centre of Biomedical Research, SGPGIMS Campus, Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
  • De A; Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, West Bengal, India.
  • Samanta A; Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, West Bengal, India.
  • Nath S; Department of Biotechnology, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Prakash A; Department of Biotechnology, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Gosipatala SB; Department of Biotechnology, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
  • Chand G; Department of Endocrine Surgery, SGPGIMS Campus, Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
  • Saha S; Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India. Electronic address: sudiptapharm@gmail.com.
Pharmacol Res ; 132: 188-203, 2018 06.
Article em En | MEDLINE | ID: mdl-29229353
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tiazinas / Neoplasias Colorretais / Ciclo-Oxigenase 2 / Fator de Transcrição STAT3 / Janus Quinase 2 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tiazinas / Neoplasias Colorretais / Ciclo-Oxigenase 2 / Fator de Transcrição STAT3 / Janus Quinase 2 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia