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Effects of an Extended Cage-change Interval on Ammonia Levels and Reproduction in Mongolian Gerbils (Meriones unguiculatus).
McCullagh, Elizabeth A; McCullagh, Peter; Klug, Achim; Leszczynski, Jori K; Fong, Derek L.
Afiliação
  • McCullagh EA; Department of Physiology and Biophysics, School of Medicine, University of Colorado Denver, Aurora, Colorado.
  • McCullagh P; Department of Statistics, University of Chicago, Chicago, Illinois.
  • Klug A; Department of Physiology and Biophysics, School of Medicine, University of Colorado Denver, Aurora, Colorado.
  • Leszczynski JK; Office of Laboratory Animal Resources, Office of Laboratory Animal Resources, Department of Pathology, School of Medicine, University of Colorado Denver, Aurora, Colorado.
  • Fong DL; Office of Laboratory Animal Resources, Office of Laboratory Animal Resources, Department of Pathology, School of Medicine, University of Colorado Denver, Aurora, Colorado;, Email: derek.fong@ucdenver.edu.
J Am Assoc Lab Anim Sci ; 56(6): 713-717, 2017 Nov 01.
Article em En | MEDLINE | ID: mdl-29256365
ABSTRACT
Prompted by the cage cleanliness of Mongolian gerbils (Meriones unguiculatus), we evaluated a prolonged cage-change interval. We compared the effects of a 2-wk and 6-wk cage-change schedule on ammonia levels, temperature, humidity, and reproductive performance in breeding pairs housed in IVC. We hypothesized that ammonia levels would remain below our threshold for cage changing and that reproductive performance would not be affected. Although ammonia levels increased over time, they remained low (less than 5 ppm) over the 6-wk period. In addition, the 6-wk cage-change interval did not significantly influence reproductive parameters, such as average pup weaning weight, number of litters, and number of pups per litter. We conclude that an extended cage-change interval (6-wk) can be used for gerbils without significant increases in intracage ammonia levels or effects on reproduction.
Assuntos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Urina / Gerbillinae / Amônia / Abrigo para Animais Limite: Animals Idioma: En Revista: J Am Assoc Lab Anim Sci Assunto da revista: MEDICINA VETERINARIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Urina / Gerbillinae / Amônia / Abrigo para Animais Limite: Animals Idioma: En Revista: J Am Assoc Lab Anim Sci Assunto da revista: MEDICINA VETERINARIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2017 Tipo de documento: Article