Sham Feeding with Bacon Does Not Alter Transit Time or Complete Examination Rate During Small Bowel Capsule Endoscopy.
Dig Dis Sci
; 63(2): 422-428, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-29302875
ABSTRACT
BACKGROUND:
During capsule endoscopy (CE) studies, the complete examination rate (CER) can be increased by prolonging capsule battery life or reducing gastric transit time (GTT) and/or small bowel transit time (SBTT). However, despite enhanced battery life, 10% of studies remain incomplete. Previously studied interventions to reduce SBTT and enhance CER have produced conflicting results. We hypothesize that this may be a consequence of an insufficiently potent stimulus of small bowel motility.AIMS:
To examine whether potent stimulation of the cephalic response of digestion during small bowel CE reduces GTT and/or SBTT and thus increases the CER.METHODS:
A single-blind randomized trial was performed to evaluate the effect of bacon sham feeding on GTT, SBTT and CER.RESULTS:
Baseline characteristics were similar between 63 sham fed patients and 59 controls. The median GTT was 17 min (9-65) in the bacon group and 25 min (14-55) in the control group. The median SBTT was 199 min (119-316) and 222 min (151-287), respectively. Cox proportional hazards model demonstrated no significant difference between groups for GTT (rate ratio 1.03, 95% CI 0.71-1.51, P = 0.87) or SBTT (rate ratio 1.02, 95% CI 0.70-1.49, P = 0.93). Although the taste of bacon was considered favorably by 72% of participants, taste did not correlate with GTT (ρ = 0.03, P = 0.83) or SBTT (ρ = - 0.115, P = 0.33). The CER was 91 and 95% in the bacon and control groups, respectively (P = 0.35).CONCLUSION:
Bacon sham feeding has no effect on GTT, SBTT or CER and cannot be recommended in clinical practice.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Trânsito Gastrointestinal
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Endoscopia por Cápsula
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Produtos da Carne
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Animals
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Female
/
Humans
/
Male
Idioma:
En
Revista:
Dig Dis Sci
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos