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Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
Shavlakadze, Tea; Zhu, Jiang; Wang, Sharon; Zhou, Weihua; Morin, Bret; Egerman, Marc A; Fan, Lin; Wang, Yanqun; Iartchouk, Oleg; Meyer, Angelika; Valdez, Reginald A; Mannick, Joan B; Klickstein, Lloyd B; Glass, David J.
Afiliação
  • Shavlakadze T; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Zhu J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Wang S; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Zhou W; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Morin B; Genomics Novartis Foundation, San Diego, California.
  • Egerman MA; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Fan L; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Wang Y; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Iartchouk O; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Meyer A; Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Valdez RA; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Mannick JB; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Klickstein LB; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Glass DJ; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
J Gerontol A Biol Sci Med Sci ; 73(7): 845-852, 2018 06 14.
Article em En | MEDLINE | ID: mdl-29304191
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Serina-Treonina Quinases TOR / Everolimo / Alvo Mecanístico do Complexo 1 de Rapamicina / Rim Limite: Animals / Humans / Male Idioma: En Revista: J Gerontol A Biol Sci Med Sci Assunto da revista: GERIATRIA Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Serina-Treonina Quinases TOR / Everolimo / Alvo Mecanístico do Complexo 1 de Rapamicina / Rim Limite: Animals / Humans / Male Idioma: En Revista: J Gerontol A Biol Sci Med Sci Assunto da revista: GERIATRIA Ano de publicação: 2018 Tipo de documento: Article